10 Best Pet Urine Removers 2025 in the United States

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is an enzyme-based cleaner designed to tackle tough pet-related stains and odors. One of its standout features is its enzyme-activated formula, which effectively breaks down organic matter like urine and vomit, ensuring that both the stain and the accompanying smell are completely eliminated. This makes it a great option for households with pets, as it can be used on a variety of surfaces, including carpets, floors, furniture, and more. It's certified safe for pets and children, meaning you can use it without worrying about harmful chemicals lingering in your home.

There are a few things to keep in mind. While the product has a good reputation for odor neutralization and stain removal, it may require multiple applications for particularly stubborn stains, which can be a bit time-consuming. Additionally, although it's designed for all surfaces, it's wise to pre-test on hidden areas to avoid any potential discoloration.

In terms of ease of use, the spray bottle design makes application straightforward, but users should follow the instructions carefully to achieve the best results. The drying time is generally quick, which is beneficial for busy pet owners. This product is particularly well-suited for pet owners dealing with accidents from dogs and cats, as well as those who want a safe, effective solution for cleaning up after their furry friends. Its performance and safety features make it a solid addition to your cleaning supplies, especially if you have multiple pets or older animals that might have occasional accidents.

The Rocco & Roxie Extreme Stain & Odor Eliminator is a strong, enzyme-based cleaner designed to handle tough pet messes like urine, vomit, and feces. It uses a bio-enzymatic formula combined with mineral odor neutralizers, which helps break down stains and odors deeply rather than just masking them. This makes it especially effective for stubborn smells and stains on carpets, floors, furniture, pet bedding, and even travel crates.

The product is safe for use around pets and children when used as directed, as it is chlorine-free and leaves no residue. It has earned a Seal of Approval from the Carpet and Rug Institute, which speaks to its gentle yet effective nature on various surfaces. The subtle lemon scent is a nice touch, fading quickly so it doesn’t overpower your home.

Users generally find it easy to apply, though drying time can vary depending on the surface and amount used, which is normal for enzyme cleaners. Some might find the price a bit higher than basic cleaners, but the high number of positive reviews and the manufacturer’s satisfaction guarantee add confidence. This product is ideal for pet owners looking for a reliable, safe solution to deep-clean and neutralize strong odors and stains without harsh chemicals.

The Rocco & Roxie Stain & Odor Eliminator is a solid choice for anyone dealing with tough pet stains and odors, especially from cats and dogs. Its enzyme-based formula is designed to break down urine and organic messes deeply, which means it doesn’t just mask smells but actually eliminates them. It works well on a variety of surfaces including carpets, furniture, floors, and even pet bedding, making it versatile for use around your home.

Safety is a strong point here — it’s chlorine-free and certified safe for pets and children, with no harsh chemicals or residues, so you can feel more comfortable using it in living areas. Users have praised how effectively it removes stubborn stains and odors, and the product has earned approval from the Carpet and Rug Institute for being gentle on carpets.

The spray comes in a convenient 32-ounce bottle that’s easy to apply, though some might find the drying time a bit longer compared to simpler cleaners, which is typical for enzyme-based products. A possible downside is that it may require multiple applications for very old or deeply set stains, but this is common for such cleaners. If you're looking for a dependable, pet-safe solution to tackle urine stains and odors around the house, this product offers a good balance of power and safety without complicated steps.