10 Best Pet Urine Removers 2025 in the United States

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is an enzyme-based cleaner designed to tackle tough pet-related stains and odors. One of its standout features is its enzyme-activated formula, which effectively breaks down organic matter like urine and vomit, ensuring that both the stain and the accompanying smell are completely eliminated. This makes it a great option for households with pets, as it can be used on a variety of surfaces, including carpets, floors, furniture, and more. It's certified safe for pets and children, meaning you can use it without worrying about harmful chemicals lingering in your home.

There are a few things to keep in mind. While the product has a good reputation for odor neutralization and stain removal, it may require multiple applications for particularly stubborn stains, which can be a bit time-consuming. Additionally, although it's designed for all surfaces, it's wise to pre-test on hidden areas to avoid any potential discoloration.

In terms of ease of use, the spray bottle design makes application straightforward, but users should follow the instructions carefully to achieve the best results. The drying time is generally quick, which is beneficial for busy pet owners. This product is particularly well-suited for pet owners dealing with accidents from dogs and cats, as well as those who want a safe, effective solution for cleaning up after their furry friends. Its performance and safety features make it a solid addition to your cleaning supplies, especially if you have multiple pets or older animals that might have occasional accidents.

ANGRY ORANGE Pet Odor Eliminator is designed to tackle tough odors from pet urine, feces, and vomit quickly, using the natural power of orange oil for a fresh citrus scent. While it doesn’t specifically mention an enzyme-based formula, its ability to neutralize odors at their source makes it effective for strong smells. It works best on hard and sealed surfaces like floors, which covers many common pet mess areas, but it may not be ideal for use on carpets or fabrics where enzyme cleaners usually shine.

The product is formulated without harsh chemicals, parabens, or sulfates, making it safer for homes with pets and children when used as directed. Users will appreciate its pleasant scent that avoids the chemical smell typical of some cleaners. The spray comes in a convenient 24 oz bottle and dries fairly quickly, allowing for easy cleanup without long waiting times.

If your main concern is deep stain removal, especially on carpets, you might need a product specifically labeled as enzyme-based, since this one focuses more on odor elimination rather than intensive stain breakdown. ANGRY ORANGE is a strong choice for pet owners looking to freshen up hard surfaces and remove stubborn odors while avoiding harsh chemicals.

Nature’s Miracle Advanced Stain And Odor Eliminator is designed especially for pet owners dealing with tough messes. Its enzymatic formula is a strong point, effectively breaking down stains and odors caused by pets. This makes it a reliable choice for those who need to tackle severe incidents, such as accidents on carpets or furniture. The product is versatile enough to be used on various surfaces, including hard floors and clothing, which adds to its appeal.

One of the standout features is its ability to discourage pets from re-soiling by neutralizing odors completely. This could be a game-changer for pet owners looking to prevent future mishaps in the same spot. Additionally, the light fresh scent helps to make the cleaning process more pleasant, masking any lingering odors while the product works.

Ease of use is another plus, as it comes in a liquid form that can be easily applied. The fast-drying feature is also convenient, as it allows you to return to your usual activities without long interruptions. However, users should be aware of the drying time, as it may vary based on the surface and mess severity. While this product excels in many areas, there are some considerations to keep in mind. Firstly, the scent might not be suitable for everyone, especially those sensitive to fragrances. Also, while it’s safe for pets and children, always exercise caution and ensure proper ventilation when using cleaning products. Some users may prefer an unscented option, depending on their sensitivities.