10 Best Enzyme Stain Removers 2025 in the United States

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is a versatile enzyme stain remover that is especially beneficial for pet owners dealing with stubborn stains and odors from urine, feces, and vomit. It uses natural enzymes that activate on contact with stains and odors, effectively breaking down and eliminating them. This product is gentle and safe to use around pets and children, being chlorine-free and color-safe.

It’s also been certified by the Carpet and Rug Institute, ensuring it does not damage carpets or leave behind any residue. This makes it suitable for a wide range of surfaces, including carpets, floors, furniture, clothing, and pet living areas. The product comes in a 32oz spray bottle, which is user-friendly and convenient for application. However, some users may find the original scent either neutral or not particularly appealing.

The eco-friendliness of this product adds another layer of appeal, as it does not contain hazardous chemicals. Nonetheless, the main drawback is its relatively higher price point, which might not fit every budget. Despite this, the satisfaction guarantee and refund policy provided by the manufacturer offer additional peace of mind for users. This product is a solid choice for those who prioritize effective and safe cleaning solutions for pet-related stains and odors.

The Puracy Stain Remover is a versatile and eco-friendly option for tackling a variety of stains on different fabric types. One of its key strengths is its gentle yet effective formulation, which can handle both fresh and set-in stains from common culprits like grass, red wine, makeup, and oil. This makes it particularly useful for households with children and pets, where accidents are more likely to happen.

The formula is free from harsh chemicals such as sulfates, parabens, bleaches, and petrochemicals, ensuring safety for both users and the environment. This could appeal to eco-conscious consumers and those with sensitive skin or allergies. Additionally, the product is designed for universal fabric compatibility, making it suitable for everything from delicate linens to sturdy upholstery, which adds to its versatility.

The 12 oz size is convenient for travel and everyday use, but may not be sufficient for larger households or heavy-duty stain removal needs. This product is well-suited for individuals looking for a safe, eco-friendly, and versatile stain remover that can be used across various fabrics and stains, although it may not cater to those with specific enzyme requirements or a preference for scented cleaners.

Nature’s Miracle Advanced Stain and Odor Eliminator stands out for its powerful enzymatic formula designed to tackle severe dog messes, including urine, diarrhea, and vomit. Its key strength lies in its ability to continue working as long as any bio-based mess is present, ensuring thorough cleaning. This formula also helps in discouraging resoiling, which is a big plus for pet owners dealing with recurring accidents.

The light, fresh scent is an added bonus, leaving your home smelling clean and fresh after use. However, it's important to mention that while the product is labeled as 'unscented' in the specs, it does contain a fresh fragrance, which might be a point of confusion for some users. Additionally, the product is safe for use around pets and in homes when used as directed, which is a significant advantage for pet owners.

The liquid sprayer form ensures easy application, making the cleaning process straightforward and hassle-free. The eco-friendliness of the product isn't explicitly highlighted, and those looking for a more environmentally-friendly option might need to consider this aspect. Nature’s Miracle is a trusted brand and this product lives up to its reputation by effectively removing tough pet stains and odors.